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In the experiment, a loud noise is heard via headphones. As a result, the test subjects experience a startle response, which is recorded with electrodes through the contraction of facial muscles.

If a weaker stimulus is emitted beforehand as a "prepulse", the startle response is lower. Filters separate what is important from what is not important and prevent sensory overload," says Dr.

In our subjects, this filtering function of the brain was significantly reduced following a sleepless night. Accordingly, their sense of time and sense of smell were altered and mental leaps were reported.

Many of those who spent the night even had the impression of being able to read thoughts or notice altered body perception. Sleep deprivation as a model system for mental illnesses The scientists see an important potential application for their results in research for drugs to treat psychoses.

However, these convey the symptoms of psychoses in only a very limited manner," says Prof. Sleep deprivation may be a much better model system because the subjective symptoms and the objectively measured filter disorder are far more akin to mental illnesses.

Of course, the sleep deprivation model is not harmful: There is also a need for research with regard to persons who regularly have to work at night.

Sleep deprivation disrupts prepulse inhibition and induces psychosis-like symptoms in healthy humans, The Journal of Neuroscience, DOI: Contact Electronic Directory Locations.

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Three new monitor lizards from the Philippines described. New weapon against highly resistant microbes within grasp. Huge amber deposit discovered in India.

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Physicists discover a new kind of celestial bodies. An excavation is no camping trip. Researchers decode a puzzling movement disorder.

Wellness for dairy cows. A new theory on the formation of the oldest continents. A new short cut for stem cell programming.

Cone snail venom controls pain. Therapeutic approach for patients with severe depression. Ripe for biomedical applications. International Researchers Bring the Rhine to the Fore.

Genetic Markers for Tracking Species. An Unexpected Virus Reservoir. Joint professorship for peace and conflict research planned.

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